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Hisao Ogawa Selected Research

MAP Kinase Kinase Kinase 5

6/2015ASK1 is involved in cognitive impairment caused by long-term high-fat diet feeding in mice.
3/2014Apoptosis signal-regulating kinase 1 is a novel target molecule for cognitive impairment induced by chronic cerebral hypoperfusion.
2/2012Novel mechanism of angiotensin II-induced cardiac injury in hypertensive rats: the critical role of ASK1 and VEGF.
1/2011Apoptosis signal-regulating kinase 1 deficiency eliminates cardiovascular injuries induced by high-salt diet.
9/2009Critical role of apoptosis signal-regulating kinase 1 in aldosterone/salt-induced cardiac inflammation and fibrosis.
11/2008Excess salt causes cerebral neuronal apoptosis and inflammation in stroke-prone hypertensive rats through angiotensin II-induced NADPH oxidase activation.

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Hisao Ogawa Research Topics

Disease

100Myocardial Infarction
02/2022 - 06/2002
75Heart Failure
09/2022 - 05/2002
73Coronary Artery Disease (Coronary Atherosclerosis)
10/2022 - 09/2003
52Cardiovascular Diseases (Cardiovascular Disease)
02/2022 - 07/2002
39Hemorrhage
09/2022 - 11/2008
34Acute Coronary Syndrome
02/2021 - 08/2005
32Hypertension (High Blood Pressure)
02/2022 - 05/2002
31Atrial Fibrillation
09/2022 - 01/2008
30Spasm (Spasms)
01/2022 - 01/2002
30Thrombosis (Thrombus)
11/2021 - 05/2003
29Atherosclerosis
11/2022 - 01/2003
27Type 2 Diabetes Mellitus (MODY)
01/2021 - 05/2005
26Inflammation (Inflammations)
06/2022 - 01/2005
25Stroke (Strokes)
11/2021 - 10/2006
23Diabetes Mellitus
02/2021 - 05/2004
19Fibrosis (Cirrhosis)
11/2016 - 02/2003
18Unstable Angina
01/2022 - 10/2003
16Atherosclerotic Plaque (Atheroma)
02/2021 - 07/2004
14Death (Near-Death Experience)
01/2022 - 09/2011
13Coronary Disease (Coronary Heart Disease)
09/2022 - 04/2006
13Myocardial Ischemia (Ischemic Heart Diseases)
03/2019 - 04/2004
13Cardiomegaly (Heart Hypertrophy)
01/2018 - 02/2003
12Stable Angina
10/2021 - 07/2002
12Chronic Renal Insufficiency
01/2021 - 09/2010
11Ischemic Stroke
01/2021 - 08/2011
11Chest Pain (Chest Pains)
09/2015 - 09/2003
10Dyslipidemias (Dyslipidemia)
01/2022 - 08/2013
10Tachycardia (Tachyarrhythmias)
01/2019 - 06/2005
10Infarction (Infarctions)
09/2018 - 10/2003
10Ventricular Tachycardia
05/2018 - 09/2006
9Pathologic Constriction (Stenosis)
01/2022 - 02/2004
9ST Elevation Myocardial Infarction
01/2021 - 12/2010
9Heart Arrest (Cardiac Arrest)
01/2020 - 12/2006
9Metabolic Syndrome (Dysmetabolic Syndrome X)
11/2016 - 09/2006
9Left Ventricular Dysfunction
09/2016 - 05/2002
8Ventricular Fibrillation
05/2018 - 09/2006
8Coronary Vasospasm (Coronary Artery Vasospasm)
09/2017 - 01/2002
7Ischemia
10/2015 - 03/2006
7Insulin Resistance
01/2013 - 07/2003
6Neoplasms (Cancer)
06/2021 - 01/2011
6Cognitive Dysfunction
01/2021 - 09/2011
6Dilated Cardiomyopathy (Cardiomyopathy, Congestive)
01/2018 - 04/2006
6Body Weight (Weight, Body)
11/2016 - 07/2008
6Hypertrophic Cardiomyopathy (Hypertrophic Obstructive Cardiomyopathy)
09/2016 - 05/2002

Drug/Important Bio-Agent (IBA)

41Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA
10/2022 - 06/2004
35Aspirin (Acetylsalicylic Acid)FDA LinkGeneric
11/2022 - 08/2007
20omega-Chloroacetophenone (Mace)IBA
10/2021 - 09/2007
20Clopidogrel (Plavix)FDA Link
01/2021 - 07/2011
19Acetylcholine (Acetylcholine Chloride)FDA Link
11/2016 - 07/2002
18Brain Natriuretic Peptide (Natrecor)FDA Link
09/2020 - 05/2002
16Glucose (Dextrose)FDA LinkGeneric
01/2014 - 04/2005
15AnticoagulantsIBA
11/2021 - 11/2012
14Calcium Channel Blockers (Blockers, Calcium Channel)IBA
01/2022 - 10/2006
14Biomarkers (Surrogate Marker)IBA
01/2018 - 07/2006
14AdiponectinIBA
08/2014 - 05/2004
13Angiotensin Receptor AntagonistsIBA
10/2022 - 09/2003
13LipidsIBA
10/2022 - 01/2006
13RivaroxabanIBA
09/2022 - 01/2017
13SaltsIBA
02/2022 - 03/2007
11C-Reactive ProteinIBA
06/2022 - 04/2004
11Prasugrel HydrochlorideFDA Link
01/2021 - 05/2012
11Cytochrome P-450 CYP2C19IBA
01/2018 - 03/2011
10NitratesIBA
08/2020 - 09/2003
9LDL CholesterolIBA
10/2022 - 09/2014
9oxidized low density lipoproteinIBA
01/2018 - 09/2007
9ThioredoxinsIBA
12/2008 - 09/2003
8CreatinineIBA
09/2022 - 07/2002
8Valsartan (Vals)FDA Link
02/2022 - 01/2007
8HDL CholesterolIBA
01/2022 - 05/2004
8Platelet Aggregation Inhibitors (Antiplatelet Drugs)IBA
11/2021 - 11/2015
8CholesterolIBA
02/2021 - 05/2004
8GadoliniumIBA
01/2018 - 05/2014
8AldosteroneIBA
12/2017 - 05/2002
8NADPH Oxidases (NAD(P)H oxidase)IBA
03/2014 - 03/2006
8Superoxides (Superoxide)IBA
06/2012 - 10/2006
7Atorvastatin (Lipitor)FDA Link
02/2021 - 01/2012
7Troponin T (Troponin T1)IBA
01/2018 - 01/2013
7Pharmaceutical PreparationsIBA
02/2016 - 01/2008
7Angiotensin IIIBA
06/2014 - 10/2007
6Angiotensin-Converting Enzyme Inhibitors (ACE Inhibitors)IBA
10/2022 - 04/2009
6Proteins (Proteins, Gene)FDA Link
06/2022 - 12/2008
6Rosuvastatin Calcium (Crestor)FDA Link
02/2022 - 07/2011
6Ezetimibe (Zetia)FDA Link
02/2021 - 10/2010
6TroponinIBA
01/2021 - 01/2013
6Creatine Kinase (Creatine Phosphokinase)IBA
09/2020 - 01/2004
6DiureticsIBA
08/2020 - 01/2010
62'- deoxythymidylyl- (3'- 5')- 2'- deoxyadenosine (d(AT))IBA
01/2020 - 05/2002
6Hemoglobins (Hemoglobin)IBA
01/2020 - 05/2014
6Thromboplastin (Tissue Factor)IBA
01/2018 - 05/2003
6Natriuretic PeptidesIBA
12/2017 - 05/2002
6apixabanIBA
01/2017 - 08/2011
6candesartanIBA
04/2016 - 10/2007

Therapy/Procedure

105Therapeutics
10/2022 - 07/2002
48Percutaneous Coronary Intervention
09/2022 - 10/2003
26Stents
01/2020 - 07/2005
9Catheter Ablation
02/2018 - 01/2008
8Coronary Artery Bypass (Coronary Artery Bypass Surgery)
01/2019 - 01/2014
7Aftercare (After-Treatment)
01/2017 - 03/2005
6Secondary Prevention
02/2022 - 05/2010
6Catheters
01/2019 - 05/2002